REFATAB-400 Tablets

REFATAB-400 contains Rifaximin 400 mg, a modern gut-selective antibiotic specially designed to act locally in the gastrointestinal tract. It is highly effective against all major enteric pathogens, while remaining safe, non-systemic, and GI-friendly.

Unlike conventional antibiotics such as ciprofloxacin, REFATAB-400 works only inside the gut, with minimal absorption into the bloodstream, resulting in low risk of systemic side effects, drug interactions, or antibiotic resistance. Most importantly, it preserves the normal gut flora, making it an ideal choice for recurrent or long-term gastrointestinal conditions.

✨ REFATAB-400 – Powerful on pathogens, gentle on your gut.

🌟 Key Benefits of REFATAB-400

• 🦠 Broad-Spectrum Gut Activity – Effective against all important enteric pathogens

• 🛡 No Systemic Absorption – Acts locally in the intestine for superior safety

• 🔄 Low Risk of Resistance – Minimal impact on bacterial resistance development

• 🌿 GI-Friendly Antibiotic – Preserves healthy colonic gut flora

• ⚖ Safer Alternative to Ciprofloxacin – Reduced systemic side effects

• 🧠 Supports Brain–Gut Health – Effective in hepatic encephalopathy

• 💊 Well-Tolerated – Suitable for repeated or long-term use under supervision

🔬 How REFATAB-400 Works

Rifaximin works by inhibiting bacterial RNA synthesis within the gut lumen. Because it is poorly absorbed, its action remains confined to the gastrointestinal tract, where it:

• Eliminates harmful bacteria

• Reduces bacterial toxin production

• Improves intestinal balance

• Lowers ammonia-producing bacteria in liver disease

• Reduces gut inflammation and bloating

This localized mechanism makes REFATAB-400 especially useful in chronic, functional, and recurrent GI disorders.

🩺 Indications – When to Use REFATAB-400

REFATAB-400 is recommended for the treatment and management of:

• 🚽 Non-Invasive Bacterial Diarrhoea

• 🧠 Hepatic Encephalopathy – Reduces ammonia-producing gut bacteria

• 🦠 Small Intestinal Bacterial Overgrowth (SIBO)

• 😣 Irritable Bowel Syndrome (IBS) – Especially IBS with bloating and diarrhea

• 🧬 Uncomplicated Diverticular Disease

• 🤢 Chronic or Recurrent Gut Infections

📋 Dosage & Administration

Dosage and duration vary depending on indication. Always follow medical advice.

👤 Who Can Benefit from REFATAB-400?

• Patients with recurrent diarrhea or IBS

• Individuals with liver disease and hepatic encephalopathy

• Patients intolerant to systemic antibiotics

• Those requiring gut-selective therapy

• People needing long-term or repeat antibiotic courses

• Patients concerned about antibiotic resistance

⚠️ Precautions

• Not indicated for invasive diarrhea with fever or blood in stools

• Use cautiously in severe liver impairment (dose adjustment may be required)

• Avoid unnecessary prolonged use without medical supervision

• Inform doctor about other medications being taken

• Store below 25°C, away from moisture

📦 Product Information

🙋 Frequently Asked Questions (FAQs)

❓ What is REFATAB-400 used for?

REFATAB-400 is used to treat bacterial diarrhea, IBS, SIBO, diverticular disease, and hepatic encephalopathy by targeting harmful gut bacteria.

❓ How is REFATAB-400 different from ciprofloxacin?

Unlike ciprofloxacin, REFATAB-400 does not get absorbed systemically, has fewer side effects, lower resistance risk, and does not disturb normal gut flora.

❓ Is REFATAB-400 safe for long-term use?

Yes. Because of its local gut action and low absorption, it is considered safe for repeated or long-term use under medical supervision.

❓ Does it affect good bacteria in the gut?

No. REFATAB-400 is gut-selective and preserves the normal colonic flora, unlike most broad-spectrum antibiotics.

❓ Can REFATAB-400 help in IBS?

Yes. It is effective in IBS associated with bloating, gas, and diarrhea, especially when linked to bacterial overgrowth.

❓ Are there side effects?

REFATAB-400 is generally well tolerated. Mild effects may include nausea, abdominal discomfort, or headache in rare cases.